Nguyen Thi Mong Diep *

* Corresponding author (diepdhqn_bak@ymail.com)

Main Article Content

Abstract

Sperm are germinal cells whose main functions, motility and acrosome reaction, promote its essential role: the oocyte fertilization. Currently, many chemicals are added to the media to enhance sperm quality during artificial insemination. Metformin, which is commonly used for the treatment of type II diabetes, possesses properties impacting cell metabolism control that have not been assessed yet in sperm. The aims of this experiment were to: (a) determine the effects of Metformin on fresh chicken sperm motility and ability to perform acrosome reaction: (b) evaluate its effects on the functions of cryopreserved sperm. These experiments have shown that the presence of Metformin in fresh semen has a positive impact on the quality of sperm and help reducing the gradual decline in sperm motility caused by cryopreservation. 
Keywords: Acrosome reaction, AMPK, chicken sperm, Metformin, sperm motility

Article Details

References

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