Isolation and identification of triterpenoid compounds from Couroupita guianensis Aubl.
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Abstract
In this report, the extracts from the fruit and leaves of Couroupita guianensis were isolated using chromatographic methods and investigated for chemical composition. Four triterpenoid compounds were isolated and identified as betulinic acid, oleanolic acid, β-amyrin and friedelin. Their chemical structures were interpreted based on modern spectra such as MS, NMR and compared with previously published spectral data.
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References
Begum, R., Rahman, M. S., Chowdhury, A. M. S., Hasan, C. M. & Rashid, M. A. (2009). Secondary metabolites (Triterpenes) from Couroupita guianensis. Oriental Pharmacy and Experimental Medicine, 9(2), 200–205. DOI:10.3742/OPEM.2009.9.2.200
Cardoso, B. K., Oliveira, H. L .M, Melo, U. Z., Fernandez, C. M. M., Campo, C. F. A. A, Gonçalves, J. E., Jr, A. L., Romagnolo, M. B., Linde, G. A. & Gazim, Z. C. (2018). Antioxidant activity of α and β-amyrin isolated from Myrcianthes pungens leaves. Natural Product Research, 34(2), 1–5, DOI:10.1080/14786419.2018.1525715
Chirchir, K. D., Cheologoi, K. P., Omolo, O. J. & Langat, K. M. (2018). Chemical constituents of Solanum mauense (Solanaceae) and Dovyalis abyssinica (Salicaceae). International Journal of Biological and Chemical Sciences, 12(2), 999–1007. DOI:10.4314/ijbcs.v12i2.29
Chudzik, M., Korzonek-Szlacheta, I. & Krol, W. 2015. Triterpenes as potentially cytotoxic compounds. Molecules, 20(1), 1610–1625. DOI:10.3390/molecules20011610
Ho, P. H. (2003). “Vietnamese plants”- An illustrated flora of Vietnam, Vol. 2. Tre Publisher, HCM City, p.21 (in Vietnamese).
Nelson, E. K. & Wheeler, D. H., 1937. Some constituents of the Cannonball fruit (Couroupita guianensis Aubl.). Journal of the American Chemical Society, 59(12), 2499–2500. DOI:10.1021/ja01291a005
Paszel-Jaworska, A., Romaniuk, A. & Rybczynska, M. (2014). Molecular mechanisms of biological activity of oleanolic acid - A Source of inspiration for a new drugs design. Mini-Reviews in Organic Chemistry, 11(3), 330–342. DOI:10.2174/1570193X1103140915111839
Ragasa, C. Y., Jr V. E., Reyes, M. M. L., Mandia, E. H., Brkljaca, R. & Urban, S. (2015). Triterpenes from Calophyllum inophyllum Linn. International Journal of Pharmacognosy and Phytochemical Research, 7(4), 718–722. DOI:10.1016/S0040-4020(01)82592-8
Thirupathi, A., Silveira, P. C., Nesi, R. T & Pinho, R. A. (2017). β-Amyrin, a pentacyclic triterpene, exhibits anti-fibrotic, anti-inflammatory, and anti-apoptotic effects on dimethyl nitrosamine–induced hepatic fibrosis in male rats. Human and Experimental Toxicology, 36(2), 113–122. DOI:10.1177/0960327116638727
Güvenalp Z., Özbek H., Ayşe Kuruüzüm-Uz, Kazaz C. & Ömür Demirezer L. (2009). Secondary metabolites from Nepeta heliotropifolia. Turk Journal of Chemistry, 33, 667–675. DOI:10.3906/kim-0812-60