Study on folate stability during thermal processing

Nguyen Minh Thuy *

* Corresponding author (nmthuy@ctu.edu.vn)

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Received: 03 Oct 2015
Revised: 24 Feb 2016
Accepted: 30 Nov 2016
Published: 30 Nov 2016
DOI: 10.22144/ctu.jen.2016.047
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Nguyen, M. T. (2016). Study on folate stability during thermal processing. CTU Journal of Innovation and Sustainable Development , (04), 87-94. https://doi.org/10.22144/ctu.jen.2016.047
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No. 04 (2016)

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Abstract

Stability of folate at different pH (3 to 9) toward thermal (65 to 140oC) treatments was studied on a kinetic basis. Residual folate concentration after thermal treatment was measured using reverse phase liquid chromatography. A model to describe the temperature effect on folate degradation rate constant is presented with the degradation of folates followed first-order reaction kinetics. The estimated Arrhenius activation energy (Ea) values of folate thermal degradation were determined.At all pH values studied, it was found that (i) folic acid and 5-formyltetrahydrofolic acid were more thermo stable than tetrahydrofolic acid and 5-methyltetrahydrofolic acid and (ii) all folates studied had the highest stability at neutral pH (pH 7.0) or alkaline pH (pH 9.2). 
Keywords: Folate, thermal, kinetic, stability, pH

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