Ho Quoc Phong * , Yasuaki Takagi , Huynh Lien Huong , Nguyen Thanh Tuyen , Tran Minh Phu , Le Thi Minh Thuy and Cao Luu Ngoc Hanh

* Correspondence: Ho Quoc Phong (email: hqphong@ctu.edu.vn)

Main Article Content

Abstract

This study was conducted to incorporate amine functional groups on the surface of hydroxyapatite to enhance its potential application in biomedical materials. Hydroxyapatite particles (HA) were synthesized from striped catfish (Pagasianodon hypophthalmus) bone and surface modified by grafting with (3-aminopropyl)triethoxysilane (APTES). Important factors affected grafting efficiency such as concentration of APTES, water content, reaction temperature and reaction time were studied. X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) and Scanning electron microscopy (SEM) were used to confirm the grafting reaction on HA surfaces. Grafting efficiency was evaluated based on intensity of characteristic absorption peaks of APTES. The experimental results showed that amine functional groups were successfully introduced on HA surface at optimal condition of 0.2 M APTES, 0.75 wt.% water content, at 60°C and 12-hour reaction time.

Keywords: 3-aminopropyl)triethoxysilane, biocompatible materials, catfish bone, hydroxyapatite

Article Details

References

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